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Active Motif

The Masters of Epigenetics. Precision in Every Base.

In the world of gene regulation, "good enough" is never enough.
​For the high-impact research coming out of HKU, CUHK, and the Science Park, your data must be beyond question. Alpha Labs Limited is proud to be your authorized Hong Kong gateway to Active Motif—the industry’s most cited name in chromatin biology and epigenetic regulation.


From their gold-standard ChIP-IT® High Sensitivity kits to the world’s largest collection of ChIP-validated antibodies, Active Motif is designed for researchers who demand absolute specificity and reproducible enrichment. Whether you are mapping the "second code" of the genome via DNA Methylation assays or uncovering histone modifications with ChIP-Seq, we provide the tools that turn complex biological questions into definitive, publishable insights.
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Technological Leadership & Key Applications

1. Advanced Chromatin Profiling
  • CUT&Tag-IT® Express: The next-generation alternative to ChIP-Seq. It requires significantly fewer cells (as few as 1,000) and provides a higher signal-to-noise ratio with faster workflows.
  • ATAC-Seq Express: The leading method for mapping genome-wide chromatin accessibility (open vs. closed chromatin) in just a few hours.
  • ChIP-IT® High Sensitivity: Optimized for researchers working with limited sample material, such as primary cells or biopsy tissues.

2. Epigenetic Reagents & Antibodies
  • ChIP-Validated Antibodies: Over 800 antibodies specifically validated for Chromatin Immunoprecipitation, ensuring your results are reproducible and reliable.
  • AbFlex® Recombinant Antibodies: High-specificity antibodies that can be easily labeled or purified, providing consistency that traditional polyclonal antibodies lack.
  • Recombinant Proteins & Histones: The largest collection of modified histones, nucleosomes, and bromodomains for biochemical assays and drug screening.

3. DNA Methylation Analysis
  • Global & Site-Specific Assays: Tools for quantifying 5-mC and 5-hmC levels, including bisulfite conversion kits and ELISA-based quantification.
  • MeDIP & hMeDIP: Immunoprecipitation-based enrichment of methylated and hydroxymethylated DNA.
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4. Normalization & Quantitative Accuracy
  • Spike-In Normalization: Active Motif’s patented technology allows for true quantitative comparison between ChIP-Seq or CUT&Tag samples by accounting for experimental variation—a "must-have" for high-impact research.​
Active Motif Official Website
Need a quote or a technical protocol for Active Motif products? WhatsApp us at +852 9662 0635 for immediate local support.
Successful ChIP-Seq begins with high-quality chromatin. Ensure your sample preparation is flawless using our iNtRON Biotechnology extraction tools before moving to your Active Motif analysis.

F&Q

  • Q: Are your ChIP-Seq antibodies validated for both N-terminal and C-terminal epitopes?
    • A: Each antibody is validated specifically for its performance in chromatin enrichment. We provide precise mapping of the immunogen so you know exactly which part of the protein is being targeted.

  • Q: Can the Recombinant Histones be used for FRET-based assays?
    • A: Yes. Active Motif offers high-purity histones and biotinylated nucleosomes that are ideal for FRET, AlphaLISA, and other high-throughput screening assays.
 
  • Q: What is the shelf life of the ChIP-IT® Express kits?
    • A: When stored correctly (most components at -20C), the kits are stable for 6 months to 1 year.
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Mobile/WhatsApp               9662 0635
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Email                                      [email protected]

PARTNERS
Polyplus 
Active Motif
iNtRON Bio
Cytoskeleton, Inc.
Enzo Life Sciences
Major Science
Sartorius ATS
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