The Exosome Experts. Standardizing the Future of Vesicle Research.
Small vesicles. Giant breakthroughs.
In the rapidly evolving fields of liquid biopsy and regenerative medicine at HKU, CUHK, and Science Park, precision is everything. Alpha Labs Limited is proud to be your Hong Kong gateway to HansaBioMed Life Sciences—the global leader in tools for Extracellular Vesicle (EV) research.
As the first company in the world to specialize in this niche, HansaBioMed provides the standardized building blocks that researchers need to turn EV complexity into consistent data. From high-purity isolated exosomes for use as calibration standards to the innovative ExoTEST™ platforms and specialized isolation kits, we provide the tools to capture, quantify, and characterize vesicles with unmatched sensitivity.
Leading Solutions for Exosome Research
1. EV Isolation & Purification
2. Standardizing Research: EV Standards
3. Quantification & Characterization (ELISA & Beyond)
4. High-Throughput EV Isolation (TFF)
5. EV-CATCHER: Targeted EV Capture
6. Specialized Standards & Control Reagents
7. Exosome Characterization Services
In the rapidly evolving fields of liquid biopsy and regenerative medicine at HKU, CUHK, and Science Park, precision is everything. Alpha Labs Limited is proud to be your Hong Kong gateway to HansaBioMed Life Sciences—the global leader in tools for Extracellular Vesicle (EV) research.
As the first company in the world to specialize in this niche, HansaBioMed provides the standardized building blocks that researchers need to turn EV complexity into consistent data. From high-purity isolated exosomes for use as calibration standards to the innovative ExoTEST™ platforms and specialized isolation kits, we provide the tools to capture, quantify, and characterize vesicles with unmatched sensitivity.
Leading Solutions for Exosome Research
1. EV Isolation & Purification
- Pure-EV Size Exclusion Chromatography (SEC) Columns: The gold standard for isolating highly pure exosomes from biofluids (plasma, serum, urine) and cell culture media. SEC columns effectively remove bulk proteins and HDL while preserving the biological activity and morphology of the vesicles.
- ExoPure™ Precipitation Reagent: A fast and scalable solution for isolating total EVs from large volumes of sample, ideal for initial screening and downstream enrichment.
2. Standardizing Research: EV Standards
- Lyophilized Exosome Standards: HansaBioMed provides the world’s first standardized, lyophilized exosomes derived from various cell lines and biofluids. These are essential as "positive controls" for calibration, protein profiling, and nucleic acid analysis.
- Fluorescent EV Standards: Pre-labeled vesicles for the calibration of flow cytometers and Nanosight (NTA) systems, ensuring accurate size and concentration measurements.
3. Quantification & Characterization (ELISA & Beyond)
- ExoTEST™ Ready-to-use ELISA Kits: Specialized sandwich ELISA assays for the quantification and immunophenotyping of exosomes based on common markers like CD9, CD63, and CD81.
- Exo-DNA & Exo-RNA Extraction Kits: Optimized kits designed specifically to capture the low-abundance genomic material trapped within EVs, compatible with NGS and qPCR workflows.
4. High-Throughput EV Isolation (TFF)
- Tangential Flow Filtration (TFF): For labs working with large volumes of starting material (such as liters of cell culture supernatant), HansaBioMed’s TFF systems are the industry standard. TFF allows for rapid concentration and diafiltration of EVs while maintaining high yield and purity, outperforming traditional ultracentrifugation in both speed and scalability.
5. EV-CATCHER: Targeted EV Capture
- Targeted Enrichment: This innovative platform uses a proprietary method to capture specific subpopulations of exosomes based on surface protein expression. It is particularly valuable for researchers looking for "tissue-specific" exosomes (e.g., brain-derived or tumor-derived vesicles) within a complex biofluid like blood.
6. Specialized Standards & Control Reagents
- Lyophilized EVs from Pathological Sources: Beyond standard cell lines, HansaBioMed offers exosomes derived from cancer cell lines (e.g., lung, breast, prostate). These serve as critical disease-state controls for researchers developing diagnostic assays.
- Exo-Check Antibody Arrays: A quick, membrane-based array to confirm the presence of exosome markers (CD63, CD81, ALIX, etc.) and detect common contaminants like Albumin in a single experiment.
7. Exosome Characterization Services
- NTA & SEM Services: For labs that do not have access to expensive instrumentation, Alpha Labs can facilitate HansaBioMed’s service arm for Nanoparticle Tracking Analysis (NTA) and Scanning Electron Microscopy (SEM), providing professional characterization reports for publication.
Need a quote or a technical protocol for HansaBioMed products? WhatsApp us at +852 9662 0635 for immediate local support."
Are your EVs physiologically relevant? For researchers working on MSC or iPSC-derived exosomes, culturing your source cells on BioLamina human-recombinant laminins ensures a more consistent and natural exosome secretome profile.
Are your EVs physiologically relevant? For researchers working on MSC or iPSC-derived exosomes, culturing your source cells on BioLamina human-recombinant laminins ensures a more consistent and natural exosome secretome profile.
F&Q
- Q: What is the pore size of the PURE-EV SEC columns?
- A: Our Size Exclusion Chromatography (SEC) columns are optimized to elute vesicles larger than 30 nm in the early fractions, while smaller proteins and contaminants stay trapped in the resin.
- Q: Can I use TFF-Easy for virus concentration?
- A: Yes. Tangential Flow Filtration (TFF) is highly effective for concentrating any particle within the 30 nm to 200 nm range, including many viral species and extracellular vesicles.
- Q: Are the Lyophilized Exosome Standards derived from human or bovine sources?
- A: We offer both. You can select standards derived from human cell lines (COLO-1, MM1, etc.) or bovine sources, depending on your experimental control requirements.
